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Development and Optimization of Nanosomal Formulations for siRNA Delivery to the Liver

The objective of this study is to develop an effective siRNA delivery system for successful delivery to the liver for the treatment of HCV. Nanosize liposomes (nanosomes) have been prepared using a mixture of cholesterol and DOTAP. A functional siRNA was encapsulated into nanosomes following condens...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kundu, Anup K., Chandra, Partha K., Hazari, Sidhartha, Pramar, Yashoda V., Dash, Srikanta, Mandal, Tarun K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298086/
https://ncbi.nlm.nih.gov/pubmed/22119665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2011.10.023
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