A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics

Nanoparticle (NP) delivery to solid tumors has recently been questioned. To better understand the magnitude of NP tumor delivery, we reanalyzed published murine NP tumor pharmacokinetic (PK) data used in the Wilhelm et al. study. Studies included in their analysis reporting matched tumor and blood c...

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Udgivet i:Sci Adv
Main Authors: Price, Lauren S. L., Stern, Stephan T., Deal, Allison M., Kabanov, Alexander V., Zamboni, William C.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439617/
https://ncbi.nlm.nih.gov/pubmed/32832614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9249
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