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Improving paclitaxel pharmacokinetics by using tumor-specific mesoporous silica nanoparticles with intraperitoneal delivery

Mesoporous silica nanoparticles (MSNs) containing paclitaxel for intraperitoneal (i.p.) delivery were developed to exploit the tumor specific accumulation of these nanocarriers after i.p. injection and the slow release of paclitaxel from the MSNs. A 3.5-fold increase in tumor cellular drug uptake wa...

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Publicado en:Nanomedicine
Autores principales: Fu, Qiang, Hargrove, Derek, Lu, Xiuling
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115211/
https://ncbi.nlm.nih.gov/pubmed/27151564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2016.04.013
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