WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway

Senescence is a tumor suppression mechanism that is induced by several stimuli, including oncogenic signaling and telomere shortening, and controlled by the p53/p21(WAF1) signaling pathway. Recently, a critical role for secreted factors has emerged, suggesting that extracellular signals are necessar...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Binet, Romuald, Ythier, Damien, Robles, Ana I., Collado, Manuel, Larrieu, Delphine, Fonti, Claire, Brambilla, Elisabeth, Brambilla, Christian, Serrano, Manuel, Harris, Curtis C., Pedeux, Rémy
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439003/
https://ncbi.nlm.nih.gov/pubmed/19951988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1016
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