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Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance

Multidrug resistance (MDR) of tumor cells to chemotherapeutic agents is the main reason for the failure of cancer chemotherapy. Overexpression of ABCB1 transporter that actively pumps various drugs out of the cells has been considered a major contributing factor for MDR. Over the past decade, many a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Luo, Xiaofang, Teng, Qiu-Xu, Dong, Jin-Yun, Yang, Dong-Hua, Wang, Meifeng, Dessie, Wubliker, Qin, Jiang-Jiang, Lei, Zi-Ning, Wang, Jing-Quan, Qin, Zuodong, Chen, Zhe-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438908/
https://ncbi.nlm.nih.gov/pubmed/32903706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01208
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