Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance

Multidrug resistance (MDR) of tumor cells to chemotherapeutic agents is the main reason for the failure of cancer chemotherapy. Overexpression of ABCB1 transporter that actively pumps various drugs out of the cells has been considered a major contributing factor for MDR. Over the past decade, many a...

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Udgivet i:Front Pharmacol
Main Authors: Luo, Xiaofang, Teng, Qiu-Xu, Dong, Jin-Yun, Yang, Dong-Hua, Wang, Meifeng, Dessie, Wubliker, Qin, Jiang-Jiang, Lei, Zi-Ning, Wang, Jing-Quan, Qin, Zuodong, Chen, Zhe-Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438908/
https://ncbi.nlm.nih.gov/pubmed/32903706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01208
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