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Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection

C-reactive protein (CRP), a component of the innate immune system, is an antipneumococcal plasma protein. Human CRP has been shown to protect mice against infection with lethal doses of Streptococcus pneumoniae by decreasing bacteremia. in vitro, CRP binds to phosphocholine-containing substances, su...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Singh, Sanjay K., Ngwa, Donald N., Agrawal, Alok
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438579/
https://ncbi.nlm.nih.gov/pubmed/32903624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01812
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