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Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection

C-reactive protein (CRP), a component of the innate immune system, is an antipneumococcal plasma protein. Human CRP has been shown to protect mice against infection with lethal doses of Streptococcus pneumoniae by decreasing bacteremia. in vitro, CRP binds to phosphocholine-containing substances, su...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Singh, Sanjay K., Ngwa, Donald N., Agrawal, Alok
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438579/
https://ncbi.nlm.nih.gov/pubmed/32903624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01812
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