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Treatment of Pneumococcal Infection by Using Engineered Human C-Reactive Protein in a Mouse Model

C-reactive protein (CRP) binds to several species of bacterial pathogens including Streptococcus pneumoniae. Experiments in mice have revealed that one of the functions of CRP is to protect against pneumococcal infection by binding to pneumococci and activating the complement system. For protection,...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Ngwa, Donald N., Singh, Sanjay K., Gang, Toh B., Agrawal, Alok
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575696/
https://ncbi.nlm.nih.gov/pubmed/33117400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.586669
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