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The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor

The glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide-1 (GLP-1) receptor are important targets in the treatment of both type 2 diabetes mellitus (T2DM) and obesity. Originally identified for their role in desensitization, internalization and recycling of G protein-coup...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Al-Sabah, Suleiman, Adi, Lobna, Bünemann, Moritz, Krasel, Cornelius
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438548/
https://ncbi.nlm.nih.gov/pubmed/32903502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01271
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