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The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor
The glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide-1 (GLP-1) receptor are important targets in the treatment of both type 2 diabetes mellitus (T2DM) and obesity. Originally identified for their role in desensitization, internalization and recycling of G protein-coup...
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| Publicat a: | Front Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7438548/ https://ncbi.nlm.nih.gov/pubmed/32903502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01271 |
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