Φορτώνει......
Nearest-neighbor amino acids of specificity-determining residues influence the activity of engineered Cre-type recombinases
The tyrosine-type site-specific DNA recombinase Cre recombines its target site, loxP, with high activity and specificity without cross-recombining the target sites of highly related recombinases. Understanding how Cre achieves this precision is key to be able to rationally engineer site-specific rec...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Rep |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7438526/ https://ncbi.nlm.nih.gov/pubmed/32814809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70867-5 |
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