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Genome Engineering in Bacillus anthracis Using Cre Recombinase

Genome engineering is a powerful method for the study of bacterial virulence. With the availability of the complete genomic sequence of Bacillus anthracis, it is now possible to inactivate or delete selected genes of interest. However, many current methods for disrupting or deleting more than one ge...

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Main Authors: Pomerantsev, Andrei P., Sitaraman, Ramakrishnan, Galloway, Craig R., Kivovich, Violetta, Leppla, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346652/
https://ncbi.nlm.nih.gov/pubmed/16369025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.1.682-693.2006
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