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Does wild-type Cu/Zn-superoxide dismutase have pathogenic roles in amyotrophic lateral sclerosis?

Amyotrophic lateral sclerosis (ALS) is characterized by adult-onset progressive degeneration of upper and lower motor neurons. Increasing numbers of genes are found to be associated with ALS; among those, the first identified gene, SOD1 coding a Cu/Zn-superoxide dismutase protein (SOD1), has been re...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Furukawa, Yoshiaki, Tokuda, Eiichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437001/
https://ncbi.nlm.nih.gov/pubmed/32811540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-020-00209-y
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