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New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of novel colchicine derivatives obtained by structura...

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Publicat a:Molecules
Autors principals: Krzywik, Julia, Aminpour, Maral, Maj, Ewa, Mozga, Witold, Wietrzyk, Joanna, Tuszyński, Jack A., Huczyński, Adam
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435877/
https://ncbi.nlm.nih.gov/pubmed/32748887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153540
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