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New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of novel colchicine derivatives obtained by structura...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Krzywik, Julia, Aminpour, Maral, Maj, Ewa, Mozga, Witold, Wietrzyk, Joanna, Tuszyński, Jack A., Huczyński, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435877/
https://ncbi.nlm.nih.gov/pubmed/32748887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153540
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