Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents

Specific modifications of colchicine followed by synthesis of its analogues have been tested in vitro with the objective of lowering colchicine toxicity. Our previous studies have clearly shown the anticancer potential of double-modified colchicine derivatives in C-7 and C-10 positions. Here, a seri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cells
Main Authors: Majcher, Urszula, Klejborowska, Greta, Kaik, Magdalena, Maj, Ewa, Wietrzyk, Joanna, Moshari, Mahshad, Preto, Jordane, Tuszynski, Jack A., Huczyński, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262455/
https://ncbi.nlm.nih.gov/pubmed/30463236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7110216
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados