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Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial

IMPORTANCE: The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. OBJECTIVE: To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ injury in patients with septic shock. DESIGN, SETT...

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Pubblicato in:JAMA
Autori principali: Moskowitz, Ari, Huang, David T., Hou, Peter C., Gong, Jonathan, Doshi, Pratik B., Grossestreuer, Anne V., Andersen, Lars W., Ngo, Long, Sherwin, Robert L., Berg, Katherine M., Chase, Maureen, Cocchi, Michael N., McCannon, Jessica B., Hershey, Mark, Hilewitz, Ayelet, Korotun, Maksim, Becker, Lance B, Otero, Ronny M, Uduman, Junior, Sen, Ayan, Donnino, Michael W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435341/
https://ncbi.nlm.nih.gov/pubmed/32809003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.11946
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