Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation

The combination of thiamine, ascorbic acid, and hydrocortisone has recently emerged as a potential adjunctive therapy to antibiotics, infectious source control, and supportive care for patients with sepsis and septic shock. In the present manuscript, we provide a comprehensive review of the pathophy...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Moskowitz, Ari, Andersen, Lars W., Huang, David T., Berg, Katherine M., Grossestreuer, Anne V., Marik, Paul E., Sherwin, Robert L., Hou, Peter C., Becker, Lance B., Cocchi, Michael N., Doshi, Pratik, Gong, Jonathan, Sen, Ayan, Donnino, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206928/
https://ncbi.nlm.nih.gov/pubmed/30373647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-018-2217-4
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