Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial

IMPORTANCE: The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. OBJECTIVE: To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ injury in patients with septic shock. DESIGN, SETT...

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Bibliographic Details
Published in:JAMA
Main Authors: Moskowitz, Ari, Huang, David T., Hou, Peter C., Gong, Jonathan, Doshi, Pratik B., Grossestreuer, Anne V., Andersen, Lars W., Ngo, Long, Sherwin, Robert L., Berg, Katherine M., Chase, Maureen, Cocchi, Michael N., McCannon, Jessica B., Hershey, Mark, Hilewitz, Ayelet, Korotun, Maksim, Becker, Lance B, Otero, Ronny M, Uduman, Junior, Sen, Ayan, Donnino, Michael W.
Format: Artigo
Language:Inglês
Published: American Medical Association 2020
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435341/
https://ncbi.nlm.nih.gov/pubmed/32809003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.11946
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