Protease-Activated Receptor-2 Regulates Neuro-Epidermal Communication in Atopic Dermatitis

Background: Activation of protease-activated receptor-2 (PAR2) has been implicated in inflammation, pruritus, and skin barrier regulation, all characteristics of atopic dermatitis (AD), as well as Netherton syndrome which has similar characteristics. However, understanding the precise role of PAR2 o...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Buhl, Timo, Ikoma, Akihiko, Kempkes, Cordula, Cevikbas, Ferda, Sulk, Mathias, Buddenkotte, Joerg, Akiyama, Tasuku, Crumrine, Debbie, Camerer, Eric, Carstens, Earl, Schön, Michael P., Elias, Peter, Coughlin, Shaun R., Steinhoff, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435019/
https://ncbi.nlm.nih.gov/pubmed/32903402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01740
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