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Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1–induced pruritus
In humans, pruritus (itch) is a common but poorly understood symptom in numerous skin and systemic diseases. Endothelin 1 (ET-1) evokes histamine-independent pruritus in mammals through activation of its cognate G protein–coupled receptor endothelin A receptor (ETAR). Here, we have identified neural...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4038561/ https://ncbi.nlm.nih.gov/pubmed/24812665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67323 |
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