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Protease-Activated Receptor-2 Regulates Neuro-Epidermal Communication in Atopic Dermatitis

Background: Activation of protease-activated receptor-2 (PAR2) has been implicated in inflammation, pruritus, and skin barrier regulation, all characteristics of atopic dermatitis (AD), as well as Netherton syndrome which has similar characteristics. However, understanding the precise role of PAR2 o...

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Vydáno v:Front Immunol
Hlavní autoři: Buhl, Timo, Ikoma, Akihiko, Kempkes, Cordula, Cevikbas, Ferda, Sulk, Mathias, Buddenkotte, Joerg, Akiyama, Tasuku, Crumrine, Debbie, Camerer, Eric, Carstens, Earl, Schön, Michael P., Elias, Peter, Coughlin, Shaun R., Steinhoff, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435019/
https://ncbi.nlm.nih.gov/pubmed/32903402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01740
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