Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity

Patients who survive sepsis display prolonged immune dysfunction and heightened risk of secondary infection. CD4 T cells support a variety of cells required for protective immunity, and perturbations to the CD4 T cell compartment can decrease overall immune system fitness. Using the cecal ligation a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sjaastad, Frances V., Kucaba, Tamara A., Dileepan, Thamotharampillai, Swanson, Whitney, Dail, Cody, Cabrera-Perez, Javier, Murphy, Katherine A., Badovinac, Vladimir P., Griffith, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435018/
https://ncbi.nlm.nih.gov/pubmed/32903436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01786
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