Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT

Infections with the pathogenic bacterium Clostridioides (C.) difficile are coming more into focus, in particular in hospitalized patients after antibiotic treatment. C. difficile produces the exotoxins TcdA and TcdB. Since some years, hypervirulent strains are described, which produce in addition th...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Korbmacher, Michael, Fischer, Stephan, Landenberger, Marc, Papatheodorou, Panagiotis, Aktories, Klaus, Barth, Holger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435013/
https://ncbi.nlm.nih.gov/pubmed/32903430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01204
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