Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT

Infections with the pathogenic bacterium Clostridioides (C.) difficile are coming more into focus, in particular in hospitalized patients after antibiotic treatment. C. difficile produces the exotoxins TcdA and TcdB. Since some years, hypervirulent strains are described, which produce in addition th...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Korbmacher, Michael, Fischer, Stephan, Landenberger, Marc, Papatheodorou, Panagiotis, Aktories, Klaus, Barth, Holger
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435013/
https://ncbi.nlm.nih.gov/pubmed/32903430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01204
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