Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT

Infections with the pathogenic bacterium Clostridioides (C.) difficile are coming more into focus, in particular in hospitalized patients after antibiotic treatment. C. difficile produces the exotoxins TcdA and TcdB. Since some years, hypervirulent strains are described, which produce in addition th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Korbmacher, Michael, Fischer, Stephan, Landenberger, Marc, Papatheodorou, Panagiotis, Aktories, Klaus, Barth, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435013/
https://ncbi.nlm.nih.gov/pubmed/32903430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01204
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