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STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population

Cancer stem cells (CSCs) are a small subpopulation of quiescent cells with the potential to differentiate into tumor cells. CSCs are involved in tumor initiation and progression and contribute to treatment failure through their intrinsic resistance to chemo- or radiotherapy, thus representing a subs...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Canesin, Giacomo, Maggio, Valentina, Palominos, Macarena, Stiehm, Anna, Contreras, Hector R., Castellón, Enrique A., Morote, Juan, Paciucci, Rosanna, Maitland, Norman J., Bjartell, Anders, Hellsten, Rebecka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434889/
https://ncbi.nlm.nih.gov/pubmed/32811873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70948-5
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