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The STAT3 inhibitor galiellalactone inhibits the generation of MDSC‐like monocytes by prostate cancer cells and decreases immunosuppressive and tumorigenic factors

BACKGROUND: The transcription factor signal transducer and activator of transcription 3 (STAT3) is implicated in cancer drug resistance, metastasis, and immunosuppression and has been identified as a promising therapeutic target for new anticancer drugs. Myeloid‐derived suppressor cells (MDSCs) play...

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書目詳細資料
發表在:Prostate
Main Authors: Hellsten, Rebecka, Lilljebjörn, Lisa, Johansson, Martin, Leandersson, Karin, Bjartell, Anders
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771992/
https://ncbi.nlm.nih.gov/pubmed/31348843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23885
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