Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice

Individual differences in cognitive decline during normal aging and Alzheimer's disease (AD) are common, but the molecular mechanisms underlying these distinct outcomes are not fully understood. We utilized a combination of genetic, molecular, and behavioral data from a mouse population designe...

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Pubblicato in:Learn Mem
Autori principali: Heuer, Sarah E., Neuner, Sarah M., Hadad, Niran, O'Connell, Kristen M.S., Williams, Robert W., Philip, Vivek M., Gaiteri, Chris, Kaczorowski, Catherine C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433658/
https://ncbi.nlm.nih.gov/pubmed/32817302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.051839.120
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