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Harnessing genetic complexity to enhance translatability of Alzheimer’s disease mouse models: a path towards experimental precision medicine
An individual’s genetic makeup plays a large role in determining susceptibility to Alzheimer’s disease (AD), but has largely been ignored in preclinical studies. To test the hypothesis that incorporating genetic diversity into mouse models of AD would improve translational potential, we combined a w...
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| Τόπος έκδοσης: | Neuron |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886697/ https://ncbi.nlm.nih.gov/pubmed/30595332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.11.040 |
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