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Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model

Across the population, individuals exhibit a wide variation of susceptibility or resilience to developing Alzheimer’s disease (AD). Identifying specific factors that promote resilience would provide insight into disease mechanisms and nominate potential targets for therapeutic intervention. Here, we...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Neuner, Sarah M., Heuer, Sarah E., Zhang, Ji-Gang, Philip, Vivek M., Kaczorowski, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372563/
https://ncbi.nlm.nih.gov/pubmed/30787942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00035
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