Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model

Across the population, individuals exhibit a wide variation of susceptibility or resilience to developing Alzheimer’s disease (AD). Identifying specific factors that promote resilience would provide insight into disease mechanisms and nominate potential targets for therapeutic intervention. Here, we...

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Vydáno v:Front Genet
Hlavní autoři: Neuner, Sarah M., Heuer, Sarah E., Zhang, Ji-Gang, Philip, Vivek M., Kaczorowski, Catherine C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372563/
https://ncbi.nlm.nih.gov/pubmed/30787942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00035
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