Lifespan-Associated Gene Expression Signatures of Recombinant BXD Mice Implicates Coro7 and Set in Longevity

Although genetic approaches have identified key genes and pathways that promote longevity, systems-level approaches are less utilized. Here, we took advantage of the wealth of omics data characterizing the BXD family of mice. We associated transcript and peptide levels across five tissues from both...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Vitiello, David, Dakhovnik, Alexander, Statzer, Cyril, Ewald, Collin Y.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299419/
https://ncbi.nlm.nih.gov/pubmed/34306034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.694033
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