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Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications†

An approach for the design of functionalized cyclic peptides is established for use in 3D cell culture and in cell targeting. Sequential orthogonal click reactions, specifically a photoinitiated thiol-ene and strain promoted azide-alkyne cycloaddition, were utilized for peptide cyclization and conju...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: LeValley, Paige J., Ovadia, Elisa M., Bresette, Christopher A., Sawicki, Lisa A., Maverakis, Emanual, Bai, Shi, Kloxin, April M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433322/
https://ncbi.nlm.nih.gov/pubmed/29863200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc03218a
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