Origin of Orthogonality of Strain-Promoted Click Reactions

Site-specific labeling of biomolecules is rapidly advancing due to the discovery of novel mutually orthogonal reactions. Quantum chemistry studies have also increased our understanding of their relative rates, although these have until now been based on highly simplified reactants. Here we examine a...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Wagner, Johannes A, Mercadante, Davide, Nikić, Ivana, Lemke, Edward A, Gräter, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600239/
https://ncbi.nlm.nih.gov/pubmed/26178299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201501727
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