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Origin of Orthogonality of Strain-Promoted Click Reactions

Site-specific labeling of biomolecules is rapidly advancing due to the discovery of novel mutually orthogonal reactions. Quantum chemistry studies have also increased our understanding of their relative rates, although these have until now been based on highly simplified reactants. Here we examine a...

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Publicat a:Chemistry
Autors principals: Wagner, Johannes A, Mercadante, Davide, Nikić, Ivana, Lemke, Edward A, Gräter, Frauke
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600239/
https://ncbi.nlm.nih.gov/pubmed/26178299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201501727
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