Exploration of multi‐target effects of 3‐benzoyl‐5‐hydroxychromen‐2‐one in Alzheimer’s disease cell and mouse models

Microtubule‐associated protein Tau, abundant in the central nervous system (CNS), plays crucial roles in microtubule assembly and stabilization. Abnormal Tau phosphorylation and aggregation are a common pathogenic hallmark in Alzheimer's disease (AD). Hyperphosphorylation of Tau could change it...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Lin, Te‐Hsien, Chiu, Ya‐Jen, Lin, Chih‐Hsin, Lin, Chung‐Yin, Chao, Chih‐Ying, Chen, Yu‐Chieh, Yang, Shu‐Mei, Lin, Wenwei, Mei Hsieh‐Li, Hsiu, Wu, Yih‐Ru, Chang, Kuo‐Hsuan, Lee‐Chen, Guey‐Jen, Chen, Chiung‐Mei
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433010/
https://ncbi.nlm.nih.gov/pubmed/32496635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13169
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