Exploration of multi‐target effects of 3‐benzoyl‐5‐hydroxychromen‐2‐one in Alzheimer’s disease cell and mouse models

Microtubule‐associated protein Tau, abundant in the central nervous system (CNS), plays crucial roles in microtubule assembly and stabilization. Abnormal Tau phosphorylation and aggregation are a common pathogenic hallmark in Alzheimer's disease (AD). Hyperphosphorylation of Tau could change it...

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Gepubliceerd in:Aging Cell
Hoofdauteurs: Lin, Te‐Hsien, Chiu, Ya‐Jen, Lin, Chih‐Hsin, Lin, Chung‐Yin, Chao, Chih‐Ying, Chen, Yu‐Chieh, Yang, Shu‐Mei, Lin, Wenwei, Mei Hsieh‐Li, Hsiu, Wu, Yih‐Ru, Chang, Kuo‐Hsuan, Lee‐Chen, Guey‐Jen, Chen, Chiung‐Mei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433010/
https://ncbi.nlm.nih.gov/pubmed/32496635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13169
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