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Residues within the Foot-and-Mouth Disease Virus 3D(pol) Nuclear Localization Signal Affect Polymerase Fidelity

Many RNA viruses encode a proof-reading deficient, low-fidelity RNA-dependent polymerase (RdRp), which generates genetically diverse populations that can adapt to changing environments and thwart antiviral therapies. 3D(pol), the RdRp of the foot-and-mouth disease virus (FMDV), is responsible for re...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Kloc, Anna, Rai, Devendra K., Gladue, Douglas P., Schafer, Elizabeth, Kenney, Mary, Rieder, Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431809/
https://ncbi.nlm.nih.gov/pubmed/32581111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00833-20
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