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Unroofing site-specific α-synuclein–lipid interactions at the plasma membrane

Parkinson’s disease is associated with α-synuclein (α-syn), a cytosolic protein enriched in presynaptic terminals. The biological function of α-syn remains elusive; however, increasing evidence suggests that the protein is involved in the regulation of synaptic vesicle fusion, signifying the importa...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kaur, Upneet, Lee, Jennifer C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430991/
https://ncbi.nlm.nih.gov/pubmed/32719116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006291117
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