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Membrane Interactions of α-Synuclein Probed by Neutrons and Photons
α-Synuclein (α-syn) is a key protein in the etiology of Parkinson’s disease. In a disease state, α-syn accumulates as insoluble amyloid fibrils enriched in β-sheet structure. However, in its functional state, α-syn adopts an amphipathic helix upon membrane association and plays a role in synaptic ve...
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| Publicado no: | Acc Chem Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7836068/ https://ncbi.nlm.nih.gov/pubmed/33415971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00453 |
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