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Molecular Details of α-Synuclein Membrane Association Revealed by Neutrons and Photons
α-Synuclein (α-syn) is an abundant neuronal protein associated with Parkinson’s disease that is disordered in solution, but exists in equilibrium between a bent- and an elongated-helix on negatively charged membranes. Here, neutron reflectometry (NR) and fluorescence spectroscopy were employed to un...
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| 發表在: | J Phys Chem B |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418488/ https://ncbi.nlm.nih.gov/pubmed/25790164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp512499r |
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