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Bulk and single-molecule analysis of a bacterial DNA2-like helicase–nuclease reveals a single-stranded DNA looping motor

DNA2 is an essential enzyme involved in DNA replication and repair in eukaryotes. In a search for homologues of this protein, we identified and characterised Geobacillus stearothermophilus Bad, a bacterial DNA helicase–nuclease with similarity to human DNA2. We show that Bad contains an Fe-S cluster...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Wilkinson, Oliver J, Carrasco, Carolina, Aicart-Ramos, Clara, Moreno-Herrero, Fernando, Dillingham, Mark S
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430649/
https://ncbi.nlm.nih.gov/pubmed/32621607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa562
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