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RADX condenses single-stranded DNA to antagonize RAD51 loading

RADX is a mammalian single-stranded DNA-binding protein that stabilizes telomeres and stalled replication forks. Cellular biology studies have shown that the balance between RADX and Replication Protein A (RPA) is critical for DNA replication integrity. RADX is also a negative regulator of RAD51-med...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhang, Hongshan, Schaub, Jeffrey M, Finkelstein, Ilya J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430644/
https://ncbi.nlm.nih.gov/pubmed/32621611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa559
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