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Combining a Candidate Vaccine for Opioid Use Disorders with Extended-Release Naltrexone Increases Protection against Oxycodone-Induced Behavioral Effects and Toxicity

Opioid use disorders (OUDs) and opioid-related fatal overdoses are a significant public health concern in the United States and worldwide. To offer more effective medical interventions to treat or prevent OUD, antiopioid vaccines are in development that reduce the distribution of the targeted opioid...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Raleigh, Michael D., Accetturo, Claudia, Pravetoni, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430456/
https://ncbi.nlm.nih.gov/pubmed/32586850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000014
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