Tumor copy-number alterations predict response to immune-checkpoint-blockade in gastrointestinal cancer

BACKGROUND: Despite the great achievements made in immune-checkpoint-blockade (ICB) in cancer therapy, there are no effective predictive biomarkers in gastrointestinal (GI) cancer. METHODS: This study included 93 metastatic GI patients treated with ICBs. The first cohort comprising 73 GI cancer pati...

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Bibliographic Details
Published in:J Immunother Cancer
Main Authors: Lu, Zhihao, Chen, Huan, Li, Shuang, Gong, Jifang, Li, Jian, Zou, Jianling, Wu, Lihong, Yu, Jianing, Han, Wenbo, Sun, Huaibo, Jiao, Xi, Zhang, Xiaotian, Peng, Zhi, Lu, Ming, Wang, Zhenghang, Zhang, Henghui, Shen, Lin
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020
Subjects:
Immunotherapy Biomarkers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430454/
https://ncbi.nlm.nih.gov/pubmed/32792358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000374
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