Cell-free DNA copy number variations predict efficacy of immune checkpoint inhibitor-based therapy in hepatobiliary cancers

BACKGROUND: This study was designed to screen potential biomarkers in plasma cell-free DNA (cfDNA) for predicting the clinical outcome of immune checkpoint inhibitor (ICI)-based therapy in advanced hepatobiliary cancers. METHODS: Three cohorts including 187 patients with hepatobiliary cancers were r...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Yang, Xu, Hu, Ying, Yang, Keyan, Wang, Dongxu, Lin, Jianzhen, Long, Junyu, Xie, Fucun, Mao, Jinzhu, Bian, Jin, Guan, Mei, Pan, Jie, Huo, Li, Hu, Ke, Yang, Xiaobo, Mao, Yilei, Sang, Xinting, Zhang, Jiao, Wang, Xi, Zhang, Henghui, Zhao, Haitao
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021
Témata:
Immunotherapy Biomarkers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112417/
https://ncbi.nlm.nih.gov/pubmed/33972389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001942
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