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Dual-Modified Liposome for Targeted and Enhanced Gene Delivery into Mice Brain

The development of neuropharmaceutical gene delivery systems requires strategies to obtain efficient and effective brain targeting as well as blood-brain barrier (BBB) permeability. A brain-targeted gene delivery system based on a transferrin (Tf) and cell-penetrating peptide (CPP) dual-functionaliz...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: dos Santos Rodrigues, Bruna, Lakkadwala, Sushant, Kanekiyo, Takahisa, Singh, Jagdish
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430450/
https://ncbi.nlm.nih.gov/pubmed/32561686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264127
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