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Dual functionalized liposome-mediated gene delivery across triple co-culture blood brain barrier model and specific in vivo neuronal transfection

Gene therapy has become a promising approach for neurodegenerative disease treatment, however there is an urgent need to develop an efficient gene carrier to transport gene across the blood brain barrier (BBB). In this study, we strategically designed dual functionalized liposomes for efficient neur...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Rodrigues, Bruna dos Santos, Oue, Hiroshi, Banerjee, Amrita, Kanekiyo, Takahisa, Singh, Jagdish
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138570/
https://ncbi.nlm.nih.gov/pubmed/30071253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.07.043
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