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Update on PARP Inhibitors in Breast Cancer

The single agent activity of PARP inhibitors (PARPi) in germline BRCA mutated (gBRCAm) breast and ovarian cancer suggests untapped potential for this new class of drug in breast cancer. The US Food and Drug Administration has approved three PARPi (olaparib, rucaparib, and niraparib) so far to treat...

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Bibliografiske detaljer
Udgivet i:Curr Treat Options Oncol
Main Authors: Zimmer, Alexandra S., Gillard, Mitchell, Lipkowitz, Stanley, Lee, Jung-Min
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430202/
https://ncbi.nlm.nih.gov/pubmed/29644491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11864-018-0540-2
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