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An update on PARP inhibitors for the treatment of cancer

The development of poly (adenosine diphosphate [ADP]) ribose polymerase (PARP) inhibitors (PARPi) has progressed greatly over the last few years and has shown encouraging results in the BRCA1/2 mutation–related cancers. This article attempts to summarize the rationale and theory behind PARPi, the cl...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Benafif, Sarah, Hall, Marcia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348139/
https://ncbi.nlm.nih.gov/pubmed/25750544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S30793
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